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iShares Nasdaq US Biotechnology UCITS ETF

iShares · IE00BDZVHG35

iShares Nasdaq US Biotechnology UCITS ETF is an exchange-traded fund (ETF) from iShares, traded under the ticker BTEE (ISIN IE00BDZVHG35). It lets you buy a basket of holdings in a single trade, spreading your money across them rather than one company. At its core it is a focused, thematic fund: it concentrates on the health care part of the market,…

· Tracks the Nasdaq US Biotechnology index ?
Equity ?Distributing ?Physical ?Ireland ?
Mid-range feePays cash dividendsOwns the shares directlyUnited StatesConcentrated in a few names
Fund size (AUM) ?
€998.3M
Risk level (SRI) ?
6 / 7 · High
1-year return ?
+45.1%
Total return · to 2026-07-28
Dividend yield
0.23%
Trailing 12 months
Yearly fee (TER) ?
0.35%
All-in cost ≈ 0.35%

About this fund

What you own

The Nasdaq US Biotechnology index is the benchmark this fund aims to copy. By holding it, this fund gives you a stake in around 261 companies across United States in a single purchase.

Dividends

The fund pays dividends out to you as cash, usually a few times a year.

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You get the dividends as cash you can spend or move elsewhere, which some people like for a sense of income. If you would rather it compounded, you buy more units yourself — it will not reinvest on its own the way an accumulating version does. The same fund is often sold in both versions; what it holds underneath is identical.

How it works

The fund actually buys every share in the index it tracks (full replication).

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Owning every holding keeps things transparent — what is in the index is what the fund actually owns. It can be a touch costlier to run for indexes with thousands of tiny positions, since the fund has to buy and maintain them all. There is no swap bank involved, so there is no extra “what if the partner fails” question to weigh.

Cost

0.35%Yearly fee (TER)
0.35%All-in cost

The yearly running cost of the fund, shown as a % of your money. Lower is cheaper.

Read more

For example, a 0.20% fee works out at €0.20 a year for every €100 invested — that’s a generic illustration of the mechanic, not this fund’s own fee. It is skimmed quietly from inside the fund a little each day, so you never get a bill — but it drags on your return every year you hold. On a broad index ETF it is usually a small fraction of a percent; the gap between a cheap and a pricey fund looks tiny on day one but compounds over decades, which is why it is worth a glance.

Fund facts

Index tracked ?
Nasdaq US Biotechnology
Replication ?
Physical
Full — buys every share
Regulation ?
UCITS
Yes
Launched
Mar 2018
8-year track record
Recommended holding period
medium to long term

Performance

61.379.197.0115133202120242026

Growth of $100 invested — the line starts at $100.

iShares Nasdaq US Biotechnology UCITS ETF

End-of-day prices, rebased to a common start so the shapes are comparable. Past performance does not predict future results.

YTD+14.9%
1 year+45.1%
3 years+17.0%
5 years+5.0%

Return, year by year

-12.3
+5.6
-1.9
+32.4
'22'23'24'25
2 of 4 up yearsBest: 2025 +32.4%Worst: 2022 -12.3%Calendar-year total returns, in USD

How bumpy has it been?

20.1%
Volatility (1y) ?
How much the price swings year to year — lower is calmer.
-26.9%
Worst drop (3y) ?
The biggest fall from a peak over the last three years.
0.86
Return for the risk (3y) ?
Reward earned per unit of bumpiness.

The bigger picture

+28.0%
Since inception
Total growth since launch — about +5.0% a year.
+64.0%
Best 12 months
The strongest one-year stretch on record.
-31.4%
Worst 12 months
The weakest one-year stretch on record.
-38.6%
Worst fall on record ?
It clawed back in about 41 months.

Dividend history

This fund pays its dividends out to you (Semi Annual). Recent payments per share:

Ex-dateAmount / share
2026-06-18£0.011
2025-12-11£0.0109
2024-06-13£0.0175
2023-12-14£0.0108

What's inside

By sector ?

Health Care100.0%
Other0.2%

The 10 biggest holdings make up 41.2% of the fund — the rest is spread across roughly 251 more companies.

Top 10 holdings

#CompanyWeight
1VERTEX PHARMACEUTICALS INC8.4%
2AMGEN INC7.8%
3GILEAD SCIENCES INC6.9%
4REGENERON PHARMACEUTICALS INC4.6%
5ALNYLAM PHARMACEUTICALS INC2.8%
6REVOLUTION MEDICINES INC2.7%
7MODERNA INC2.2%
8BIOGEN INC2.1%
9ILLUMINA INC2.0%
10ROIVANT SCIENCES LTD1.7%

Where to buy this fund

Set from your language & location — change it if it's wrong.

Where it trades

ExchangeTickerCurrency
LSEBTEEUSD★ Primary
EUR listings
Euronext AmsterdamBTEEEUR
FrankfurtOM3EEUR
USD listings
B2BTEEUSDUSD
B3BTEELUSD
B4BTEEUSDUSD
E1BTEEEURUSD
E1BTEEGBXUSD
E1BTEEUSDUSD
EBBTEELUSD
EPBTEEUSDUSD
EUBTEEUSDUSD
EUBTEEGBXUSD
EUBTEEEURUSD
EZBTEEUSDUSD
GDOM3EUSD
GHOM3EUSD
GMOM3EUSD
GZOM3EUSD
IXBTEELUSD
L1BTEELUSD
L3BTEELUSD
LAOM3EUSD
London Stock ExchangeBTEEUSD
LUOM3EUSD
POBTEELUSD
QTOM3EUSD
S1BTEELUSD
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For serious comparison — full data holdings, percentiles, advanced risk, tilt, flows

Full holdings

As of 2026-07-28 · the fund's own published holdings.

#CompanyWeight
1VERTEX PHARMACEUTICALS INC8.4%
2AMGEN INC7.8%
3GILEAD SCIENCES INC6.9%
4REGENERON PHARMACEUTICALS INC4.6%
5ALNYLAM PHARMACEUTICALS INC2.8%
6REVOLUTION MEDICINES INC2.7%
7MODERNA INC2.2%
8BIOGEN INC2.1%
9ILLUMINA INC2.0%
10ROIVANT SCIENCES LTD1.7%
11ARGENX SE ADR1.7%
12ROYALTY PHARMA PLC CLASS A1.7%
13INSMED INC1.6%
14UNITED THERAPEUTICS CORP1.6%
15INCYTE CORP1.6%
16GUARDANT HEALTH INC1.5%
17VIATRIS INC1.3%
18NEUROCRINE BIOSCIENCES INC1.2%
19ASCENDIS PHARMA1.1%
20MEDPACE HOLDINGS INC1.1%
21JAZZ PHARMACEUTICALS PLC1.0%
22BRIDGEBIO PHARMA INC1.0%
23EXELIXIS INC1.0%
24IONIS PHARMACEUTICALS INC0.9%
25AXSOME THERAPEUTICS INC0.9%
26SUMMIT THERAPEUTICS INC0.8%
27MADRIGAL PHARMACEUTICALS INC0.8%
28ARROWHEAD PHARMACEUTICALS INC0.8%
29CYTOKINETICS INC0.8%
30BIOMARIN PHARMACEUTICAL INC0.8%
31KRYSTAL BIOTECH INC0.8%
32BIONTECH SE ADR0.7%
33TEMPUS AI INC CLASS A0.7%
34BEONE MEDICINES AG0.7%
35SANOFI ADR REPRESENTING SA0.7%
36HALOZYME THERAPEUTICS INC0.7%
37KYMERA THERAPEUTICS INC0.6%
38IMMUNITYBIO INC0.6%
39ALKERMES0.6%
40NUVALENT INC CLASS A0.6%
41PRAXIS PRECISION MEDICINES INC0.6%
42PROTAGONIST THERAPEUTICS INC0.6%
43APOGEE THERAPEUTICS INC0.6%
44ABIVAX AMERICAN DEPOSITARY SHARES0.6%
45VAXCYTE INC0.6%
46IMMUNOVANT INC0.5%
47SPYRE THERAPEUTICS INC0.5%
48RHYTHM PHARMACEUTICALS INC0.5%
49MIRUM PHARMACEUTICALS INC0.5%
50PTC THERAPEUTICS INC0.5%
51COGENT BIOSCIENCES INC0.5%
52SCHOLAR ROCK HOLDING CORP0.5%
53LIGAND PHARMACEUTICALS INC0.4%
54TWIST BIOSCIENCE CORP0.4%
55CG ONCOLOGY INC0.4%
56CRISPR THERAPEUTICS AG0.4%
57ERASCA INC0.4%
58XENON PHARMACEUTICALS INC0.4%
59AMNEAL PHARMACEUTICALS INC CLASS A0.4%
60TRAVERE THERAPEUTICS INC0.4%
61CARIS LIFE SCIENCES INC0.3%
62ORUKA THERAPEUTICS INC0.3%
63INDIVIOR PHARMACEUTICALS INC0.3%
64DEFINIUM THERAPEUTICS INC0.3%
6510X GENOMICS INC CLASS A0.3%
66VERACYTE INC0.3%
67CRINETICS PHARMACEUTICALS INC0.3%
68ACADIA PHARMACEUTICALS INC0.3%
69TANGO THERAPEUTICS INC0.3%
70EDGEWISE THERAPEUTICS INC0.3%
71STRUCTURE THERAPEUTICS ADR INC0.3%
72DENALI THERAPEUTICS INC0.3%
73NEWAMSTERDAM PHARMA NV0.3%
74RELAY THERAPEUTICS INC0.3%
75DYNE THERAPEUTICS INC0.3%
76BEAM THERAPEUTICS INC0.3%
77ADAPTIVE BIOTECHNOLOGIES CORP0.2%
78IDEAYA BIOSCIENCES INC0.2%
79ALUMIS INC0.2%
80ULTRAGENYX PHARMACEUTICAL INC0.2%
81ARCUTIS BIOTHERAPEUTICS INC0.2%
82ENLIVEN THERAPEUTICS INC0.2%
83GRAIL INC0.2%
84DISC MEDICINE INC0.2%
85KINIKSA PHARMACEUTICALS INTERNATIO0.2%
86TARSUS PHARMACEUTICALS INC0.2%
87VERA THERAPEUTICS INC CLASS A0.2%
88MBX BIOSCIENCES INC0.2%
89SUPERNUS PHARMACEUTICALS INC0.2%
90UNIQURE NV0.2%
91BIOCRYST PHARMACEUTICALS INC0.2%
92TREVI THERAPEUTICS INC0.2%
93NURIX THERAPEUTICS INC0.2%
94INTELLIA THERAPEUTICS INC0.2%
95MINERALYS THERAPEUTICS INC0.2%
96VERICEL CORP0.2%
97ABCELLERA BIOLOGICS INC0.2%
98KODIAK SCIENCES INC0.2%
99LEGEND BIOTECH ADR REP CORP0.2%
100PHARVARIS N V NV0.2%
101AGIOS PHARMACEUTICALS INC0.2%
102OCULAR THERAPEUTIX INC0.2%
103HARMONY BIOSCIENCES HLDG INC0.1%
104GENMAB SPONSORED ADR0.1%
105ADMA BIOLOGICS INC0.1%
106RECURSION PHARMACEUTICALS INC CLAS0.1%
107SAREPTA THERAPEUTICS INC0.1%
108STOKE THERAPEUTICS INC0.1%
109PRECIGEN INC0.1%
110AMYLYX PHARMACEUTICALS INC0.1%
111NOVOCURE LTD0.1%
112SYNDAX PHARMACEUTICALS INC0.1%
113AURINIA PHARMACEUTICALS INC0.1%
114SIONNA THERAPEUTICS INC0.1%
115MONTE ROSA THERAPEUTICS INC0.1%
116ANI PHARMACEUTICALS INC0.1%
117BICARA THERAPEUTICS INC0.1%
118IOVANCE BIOTHERAPEUTICS INC0.1%
119UROGEN PHARMA LTD0.1%
120ATAIBECKLEY INC0.1%
121ABSCI CORP0.1%
122ZYMEWORKS INC0.1%
123GH RESEARCH PLC0.1%
124TYRA BIOSCIENCES INC0.1%
125ANAPTYSBIO INC0.1%
126RAPPORT THERAPEUTICS INC0.1%
127TAYSHA GENE THERAPIES INC0.1%
128MAZE THERAPEUTICS INC0.1%
129USD CASH0.1%
130FORTREA HOLDINGS INC0.1%
131COMPASS PATHWAYS ADR PLC0.1%
132HARROW INC0.1%
133VIR BIOTECHNOLOGY INC0.1%
134ZENAS BIOPHARMA INC0.1%
135ARRIVENT BIOPHARMA INC0.1%
136INNOVIVA INC0.1%
137NOVAVAX INC0.1%
138PERSONALIS INC0.1%
139SEPTERNA INC0.1%
140XERIS BIOPHARMA HOLDINGS INC0.1%
141IMMUNOCORE HOLDINGS ADR PLC0.1%
142INHIBRX BIOSCIENCES INC0.1%
143ARDELYX INC0.1%
144MANNKIND CORP0.1%
145MEIRAGTX HOLDINGS PLC0.1%
146CORVUS PHARMACEUTICALS INC0.1%
147EYEPOINT INC0.1%
148SAVARA INC0.1%
149COLLEGIUM PHARMACEUTICAL INC0.1%
150WAVE LIFE SCIENCES LTD0.1%
151OLEMA PHARMACEUTICALS INC0.1%
152XENCOR INC0.1%
153ORIC PHARMACEUTICALS INC0.1%
154SANA BIOTECHNOLOGY INC0.1%
155BIOAGE LABS INC0.1%
156SOLID BIOSCIENCES INC0.1%
157VOR BIOPHARMA INC0.1%
158ALVOTECH SA0.1%
159CULLINAN THERAPEUTICS INC0.1%
160ETON PHARMACEUTCIALS INC0.1%
161PACIRA BIOSCIENCES INC0.1%
162KURA ONCOLOGY INC0.1%
163DESIGN THERAPEUTICS INC0.1%
164GERON CORP0.1%
165ARBUTUS BIOPHARMA CORP0.1%
166ANNEXON INC0.1%
167REPLIMUNE GROUP INC0.1%
168PHATHOM PHARMACEUTICALS INC0.1%
169THERAVANCE BIOPHARMA INC0.1%
170JANUX THERAPEUTICS INC0.1%
171AMPHASTAR PHARMACEUTICALS INC0.1%
172GRIFOLS ADR REPRESENTING ONE NON-V0.1%
173ESPERION THERAPEUTICS INC0.1%
174MARAVAI LIFESCIENCES HOLDINGS INC0.1%
175CYTOMX THERAPEUTICS INC0.1%
176ARS PHARMACEUTICALS INC0.1%
177ZEVRA THERAPEUTICS INC0.1%
178OMEROS CORP0.1%
179ACLARIS THERAPEUTICS INC0.1%
180MESOBLAST ADR REPRESENTING LTD0.1%
181REGENXBIO INC0.1%
182PRIME MEDICINE INC0.1%
183CASTLE BIOSCIENCES INC0.1%
184CANDEL THERAPEUTICS INC0.1%
185IRONWOOD PHARMA INC CLASS A0.1%
186AURA BIOSCIENCES INC0.1%
187PHIBRO ANIMAL HEALTH CORP CLASS A0.1%
188ALLOGENE THERAPEUTICS INC0.1%
1894D MOLECULAR THERAPEUTICS INC0.1%
190RIGEL PHARMACEUTICALS INC0.1%
191FIRST TRACKS BIOTHERAPEUTICS INC0.1%
192TECTONIC THERAPEUTIC INC0.1%
193CORMEDIX INC0.1%
194ZAI LABORATORY ADR REPRESENTING LT0.0%
195ALTIMMUNE INC0.0%
196EDITAS MEDICINE INC0.0%
197ARVINAS INC0.0%
198KYVERNA THERAPEUTICS INC0.0%
199PACIFIC BIOSCIENCES OF CALIFORNIA0.0%
200AQUESTIVE THERAPEUTICS INC0.0%
201PROTHENA PLC0.0%
202CABALETTA BIO INC0.0%
203CONTINEUM THERAPEUTICS INC CLASS A0.0%
204NEUROGENE INC0.0%
205C4 THERAPEUTICS INC0.0%
206SAGIMET BIOSCIENCES INC SERIES A0.0%
207ENANTA PHARMACEUTICALS INC0.0%
208KAMADA LTD0.0%
209SILENCE THERAPEUTICS ADR REPRESENT0.0%
210LAKEFRONT BIOTHERAPEUTICS ADR NV0.0%
211UPSTREAM BIO INC0.0%
212EVOLUS INC0.0%
213ROCKET PHARMACEUTICALS INC0.0%
214ATEA PHARMACEUTICALS INC0.0%
215VANDA PHARMACEUTICALS INC0.0%
216OMNIAB INC0.0%
217PUMA BIOTECHNOLOGY INC0.0%
218IMMUNEERING CORP CLASS A0.0%
219LARIMAR THERAPEUTICS INC0.0%
220LEXEO THERAPEUTICS INC0.0%
221AUTOLUS THERAPEUTICS ADR PLC0.0%
222ENTRADA THERAPEUTICS INC0.0%
223LYELL IMMUNOPHARMA INC0.0%
224NEUMORA THERAPEUTICS INC0.0%
225FOGHORN THERAPEUTICS INC0.0%
226ALPHA TEKNOVA INC0.0%
227ANAVEX LIFE SCIENCES CORP0.0%
228SIGA TECHNOLOGIES INC0.0%
229FULCRUM THERAPEUTICS INC0.0%
230INVIVYD INC0.0%
231CODEXIS INC0.0%
232AC IMMUNE SA0.0%
233VOYAGER THERAPEUTICS INC0.0%
234NOVABRIDGE BIOSCIENCES ADR0.0%
235COHERUS ONCOLOGY INC0.0%
236KEROS THERAPEUTICS INC0.0%
237ORCHESTRA BIOMED HOLDINGS INC0.0%
238ARCTURUS THERAPEUTICS HOLDINGS INC0.0%
239BICYCLE THERAPEUTICS ADR PLC0.0%
240TENAYA THERAPEUTICS INC0.0%
241GBP CASH0.0%
242LENZ THERAPEUTICS INC0.0%
243LIFECORE BIOMEDICAL INC0.0%
244QUANTUM SI INC CLASS A0.0%
245HUMACYTE INC0.0%
246CARIBOU BIOSCIENCES INC0.0%
247JYONG BIOTECH LTD0.0%
248PEPGEN INC0.0%
249PYXIS ONCOLOGY INC0.0%
250AARDVARK THERAPEUTICS INC0.0%
251BLACK DIAMOND THERAPEUTICS INC0.0%
252EUR CASH0.0%
253CASH COLLATERAL USD HSBFT0.0%
254RANI THERAPEUTICS HOLDINGS INC CLA0.0%
255AKERO THERAPEUTICS CVR0.0%
256GOSSAMER BIO INC0.0%
257THIRD HARMONIC BIO INC0.0%
258OMNIAB INC $12.50 VESTING Prvt0.0%
259OMNIAB INC $15.00 VESTING Prvt0.0%
260RUSSELL 2000 EMINI CME SEP 260.0%
261E-MINI HEALTH CARE SECTOR SEP 260.0%

⭳ Download full holdings (CSV)

How it ranks vs peers

🪙 Cheaper than 16% of similar ETFs💰 All-in cost cheaper than 8%📈 Higher 1-yr return than 97%📈 Higher 3-yr return than 53%📈 Higher 5-yr return than 12%📊 Beat its category by 26.8% (1-yr) (category average +18.3%)📊 Beat its category by 0.9% (3-yr) (category average +16.1%)📊 Behind its category by 4.6% (5-yr) (category average +9.6%)

Versus the Equity (stocks) · United States · USD ETFs we track.

Advanced risk

1.25
Sortino (3y) ?
0.63
Calmar (3y) ?
12.5%
Downside deviation ?
75%
Up months (hit rate) ?
$9.88
52-week high ?
$6.39
52-week low ?

Concentration depth

~37 ?
Effective number of holdings

Roughly 261 companies are held, but the largest names carry most of the weight — so it behaves like ~37 equal-sized positions.

Tilt vs a world tracker

Health Care+90.6
Technology-29.2
United States+21.0
Financials-16.3
Industrials-11.6
Consumer Discretionary-9.0

Percentage points over / under a broad world-equity tracker (not a licensed benchmark).

Estimated fund flows

−€2.2M
Estimated net flow, last month

Estimated from fund-size changes.

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We found 6 funds that do much the same job as this one. To pick them we matched this fund's asset class and region, then show how close each match is below.

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Index trackedNasdaq US BiotechnologyS&P 500 IndexS&P 500S&P 500S&P 500 IndexS&P 500
Yearly fee (TER)0.35%0.09%0.10%0.10%0.02%0.07%0.06%
All-in cost0.35%0.00%0.10%0.00%0.00%0.07%0.00%
Fund size€998.3M€704.3B€175.6B€154.3B€146.6B€134B€86.2B
DomicileIrelandUnited StatesIrelandIrelandUnited StatesIrelandUnited States
ReplicationPhysical (full)Physical (full)Physical (full)Physical (full)Physical (full)Physical (full)Physical (full)
3-yr return p.a.+17.0%+21.0%+17.5%+21.0%+19.4%+10.2%
5-yr return p.a.+5.0%+12.0%+10.2%+12.0%+12.8%+5.5%
# holdings261504511511508511103

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Data as of 2026-07-28 · Source: issuer data, compiled by Finance Hamster

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